The organization and application of resource is best managed in a stage-gate organizational structure (see http://www.stage-gate.com/index.php/). Each stage encompasses more than one goal and more than one discipline – a work matrix. Each gate (milestone) is an organizational decision to commit resource to the next stage. Most pharma find it useful to have one or more committees focus the organization to a decision at each milestone. There may be submilestones as well. The goals of each stage are discussed in the section Stage Related Goals.
Figure 4, Stage-Gate (Milestone) Organization of Bio/pharmaceutical R&D